Abstract Submission Guidelines
The abstract submission system can be found here: https://ebusiness.avma.org/abstracts.
Please read the instructions below before submitting your abstract.
The deadline for submission will be July 14, 2016; 3 pm Central Time
The following are instructions for completing and formatting your abstract submission. Please note that the finished poster size should not exceed 3' x 4'. More information regarding poster sessions is below.
Please note that the character limits given below include spaces (e.g. "Good Title" = 10 characters)
Abstract Title - Capitalize only the first word of the title and proper nouns. Allowable Characters: Italics, Greek symbols/math operators, subscript and superscript. Character limit = 110
Authors - Separate the author’s names with commas; do not include academic degrees or specialty certification. Please only underline the presenting author’s name. Allowable Characters: Italics, Greek symbols*/math operators, subscript and superscript. Character limit = 220
Affiliations - Enter the authors’ professional affiliations at the time of the study. Affiliations should be listed in the order in which the authors’ names are given in the byline. For authors affiliated with a university, the department, school or college, university, city, and state should be listed (in that order). If authors do not all have the same affiliation, the authors’ last names should be given in parentheses to indicate affiliation. Allowable Characters: Italics, Greek symbols*/math operators, subscript and superscript. Character limit = 330
Abstract Content - Enter the content of your abstract. Do not include blank lines or paragraph breaks. Allowable Characters: Italics, Greek symbols*/math operators, subscript and superscript. Character limit = 1750
Research Grant - Enter information on any grants or the source of any third-party funding used to conduct this research (ask your mentor). Alternatively, enter “None” if there was no third-party funding for the research or “Unknown” if you do not know the source of research funding. Character limit = 200
Student Support - Enter information on the source of your student summer research stipend. Alternatively, enter “None” if you did not receive a stipend or “Unknown” if you do not know the source of your research stipend. Character limit = 95
Field of Research - Select your field of research from the drop-down box provided.
*Note: When entering your content, only use the symbols available from the Abstract Submissions page. Use of other symbols may be lost. (I.e. α, β, γ, δ, ε, κ, λ, μ, ρ, χ, Δ, Θ, Σ)
Please review the abstract below for an example of how your submission might look in the program booklet.
P21 Up regulation during Campylobacter jejuni CDT-induced epithelial H407 cell senescence
James Gaffney, Changyou Lin, and Gerald E. Duhamel
Cornell University CVM, Ithaca, NY
Cytolethal distending toxin (CDT) is a genotoxin produced by Campylobacter jejuni (CjejCDT), a major cause of food- and water-borne zoonotic intestinal illness worldwide. CDT is a novel class of bacterial toxin with DNase activity that translocates to the nucleus of eukaryotic cells. There, it exerts genotoxic damage characterized by activation of an ATM-dependent DNA damage response (DDR) resulting in arrest of the cell cycle and apoptotic death. Previous studies in our laboratory indicate that eukaryotic cells intoxicated with sub-lethal concentrations of CjejCDT undergo irreversible arrest of the cell cycle together with cytoplasmic accumulation of β-galactosidase and secretion of proinflammatory cytokines consistent with premature senescence, a protective mechanism against cancer progression. On the basis of these observations, we hypothesized that a key upstream activator of premature senescence, the cyclin dependent kinase inhibitor p21Cip1/Waf1 (p21) regulates the decision of intoxicated cell to undergo senescence rather than apoptosis. While H407 cells incubated with control medium or medium containing whole-cell lysate (WCL) of a C. jejuni mutant strain with a disrupted CDT gene (ΔCDT) continued to grow over 7 days, cells incubated with sublethal concentrations of CjejCDT obtained from the isogenic wild-type (WT) and ΔCDT strain complemented with a full length CDT operon showed complete growth arrest and a DDR characterized by ATM-dependent phosphorylation of histone H2AX (γ-H2AX). Sequential confocal microscopy and Western blot analysis of CjejCDT-intoxicated H407 cells correlated development of nuclear DNA lesions with up-regulation of p21 and loss of cytoskeletal integrity. These findings provide a molecular basis to explain the mechanism of CDT-induced premature eukaryotic cell senescence.
Research Grant: American Heart Institute
Student Support: Morris Animal Foundation
There will be 4 poster sessions – 2 on Friday afternoon (A and B) and 2 on Saturday afternoon (C and D). Posters will be hung using pipe and drape; T pins/clips will be provided (4 per poster)
POSTER SIZE: 3’ x 4’ (the horizontal length of the poster cannot be longer than 4’)
Following are some guidelines that we give our students:
Sans-serif fonts such as Arial print and read well. If you use non-standard fonts, please send them with your file
- Title: Between 65 and 108 points
- Subheadings: ~30 - 54 points
- Body text: ~24 - 30 points
Keep contrast high between foreground elements and background. Light colored backgrounds with dark text tend to print better and are easier to read.
Imported objects, graphs and tables:
To import from Excel:
- step 1 - in Excel, select the chart, then “Edit” > “Copy”
- step 2 - in Powerpoint, “Edit” > “Paste Special” > “Excel Object”
To insert a photo:
- jpg’s are preferable.
- In Powerpoint choose “insert” > “picture” > “from file”
Keep resolution near 200-300 dots/pixels per inch at actual printed size, saved as jpg.
Organize your poster using 3 to 5 columns so that lines of text don’t exceed ~18 inches.